Weekend Reads (5/23/25)

Interesting things I found on the internet this week
weekend-reads
Author

Mike Tokic

Published

May 23, 2025

Articles

The Day You Became A Better Writer By Scott Adams

  • Removing fluff and keeping your writing simple is key.

OpenAI Rolls Out Codex, An Automated Coding Agent

  • This agent runs autonomously in the cloud to build many new software features in parallel.
  • For the longest time, I’ve been waiting for LLMs to get so good they can port my forecasting package, finnts, from R to Python. I think now I might be able to get that work started. Exciting stuff!

Videos

Dr. Rhonda Patrick on the Dr. Hyman Show

  • Vitamin D
    • What it does: Acts like a hormone, flipping 200+ genes for immune function, mood, and bone strength.
    • Problem: Indoor living leaves ~40 % of adults short.
    • Fix: Supplement 2 000–4 000 IU of vitamin D₃ daily; pair with vitamin K₂ (≈ 100 µg) so calcium goes to bones, not arteries.
  • Omega 3
    • Why care: Higher blood omega-3 can add years to life, cut triglycerides, and calm inflammation.
    • Targets: 1000–2000 mg EPA + DHA daily from fatty fish or purified fish-/algal-oil capsules.
  • Magnesium
    • Roles: Needed for 300+ enzymes, ATP energy, nerve balance, vitamin D activation.
    • Shortfall: Nearly half the population under-consumes it.
    • Dose: 200–400 mg nightly (glycinate, citrate, or malate). Bonus: deeper sleep, fewer cramps, steadier blood pressure.
  • Triage Theory
    • Minor shortages get “triaged” to urgent tasks (e.g., keeping blood clotting) while long-term maintenance (DNA repair, artery upkeep) is skipped. You feel fine today but sow seeds of cancer, heart disease, or dementia decades later.
    • Solution: keep every micronutrient in the green zone, not just “barely adequate.”
  • Multivitamins
    • Over 90 % of people miss at least one essential nutrient from food. A quality multivitamin/mineral fills common gaps safely and cheaply. Urine color doesn’t equal wasted value; it simply shows water-soluble B-vitamins passing through.
  • Personalized Nutrition
    • Variants in genes like MTHFR (folate), vitamin D receptors, or magnesium transporters can raise your optimal intake. Simple DNA tests plus blood work reveal whether you need more of certain B-vitamins, choline, or others. One-size-fits-all dosing belongs in the last century.
  • Nutrient Synergy
    • Magnesium + Vitamin D: Mg activates D; D can’t perform without it.
    • Vitamin D + K2: D boosts calcium absorption; K2 directs calcium to bones.
    • Food First: Whole foods pack these combos naturally—e.g., salmon (D + omega-3s), leafy greens (Mg + K), bell peppers (vitamin C aids iron absorption).
  • Phytochemicals
    • Sulforaphane: From broccoli sprouts; switches on Nrf2, your cell-cleanup master switch. Two servings of sprouts or a 10–20 mg extract a few times weekly can boost detox enzymes and antioxidant defenses.
    • Anthocyanins: Blue/purple pigments in berries improve brain blood flow and memory; aim for a daily cup of mixed berries or a concentrated powder.
    • Rule of Thumb: “Eat the rainbow” = free daily antioxidant therapy.
  • Processed Foods
    • Factory foods hijack appetite, spike blood sugar, and displace nutrients. In controlled trials people eat about 500 extra calories a day and gain weight on an ultra-processed diet even when meals are calorie-matched. Swap packaged snacks, sodas, and fast-food for whole-food versions; your waistline, microbiome, and inflammation markers will thank you.
  • VO2 Max
    • Cardiorespiratory fitness trumps almost every other risk factor. Moving from “poor” to “average” fitness slashes mortality risk as much as quitting smoking. Aim for at least:
      • 150 min/week moderate cardio (or 75 min vigorous), plus
      • 2–3 strength sessions to preserve muscle and bone. Mix in interval training or hiking hills to nudge VO₂ max higher—adaptation happens at every age.

Andrew Huberman’s Productivity Toolkit

Harness circadian biology for sharper focus, better mood, and deeper sleep.

Morning (Wake → Noon)

Tool Why It Works How To Do It
Log Wake-Up Time Estimates your temperature minimum (≈ 2 h before normal wake time). Later cues best focus window. Keep pen & pad on the nightstand; jot wake-up time daily.
Walk Outside Immediately Forward motion + “optic flow” calms amygdala (lower anxiety) and boosts alertness. 10–15 min brisk walk — no sunglasses.
Sunlight in Eyes Early bright light sets your circadian clock and triggers the healthy cortisol pulse. Combine with the walk; cloud cover is fine.
Hydrate + Electrolytes Neurons fire with sodium, potassium, magnesium; you wake slightly dehydrated. Big glass of water + pinch sea salt (≈ ½ tsp).
Delay Caffeine 90–120 min Prevents mid-afternoon crash from early adenosine blockade. First coffee/tea after the 90-min mark.
Fast Until Late Morning Mild adrenaline bump → tighter focus, better learning. First calories ~11 a.m.–noon (water/electrolytes only before).

90-Minute Deep-Work Block

  1. Start 4–6 h after temperature minimum (usually mid-morning).
  2. Set a 90-min timer to ride the brain’s ultradian cycle.
  3. Optimize workstation: screen at/above eye level, upright posture, low-volume white noise.
  4. Phone off (not airplane mode).

Objective: enter a “tunnel” of calm, intense focus.

Midday

Action Why Implementation
Workout Exercise boosts BDNF, immune balance, mood. Alternate: Resistance (80 % sub-failure / 20 % to failure) and Endurance (80 % easy / 20 % above lactate threshold). Keep < 60 min.
First Meal: Protein-Heavy, Lowish Carb Maintains dopamine & adrenaline for afternoon alertness. Protein + veg; add starch only if you trained.
Omega-3 Dose 1 g EPA/day supports mood like a mild antidepressant. Fish, algae oil or capsule with lunch.
Post-Meal Walk (5–30 min) Speeds glucose clearance, reinforces light cues. Step outside immediately after eating.

Afternoon

  • Light Break: 10–30 min outside. Late-day sun buffers against nighttime light disruption.
  • Second 90-min Work Block: Same tunnel protocol during your next alert peak.

Evening

Habit Purpose How
Dinner = Starchy Carbs + Protein Carbs → serotonin → melatonin → easier sleep; replenishes glycogen. Rice, potatoes, pasta, oats, plus moderate protein.
Hot Bath/Sauna (1–2 h Pre-Bed) Heats you so the body cools faster afterward, speeding sleep onset. 10–15 min hot shower, bath, or sauna.
Dark, Cool Bedroom Light & heat suppress melatonin. Black-out curtains; room ≈ 18 °C / 65 °F.
Optional Sleep Stack Eases transition without heavy drugs. 30–60 min pre-bed: 300–400 mg Mg threonate/glycinate + 50 mg apigenin + 100–200 mg L-theanine.

Night-Waking Fixes

Scenario Tactic
Wake 2–3 a.m. after forcing yourself to stay up late Go to bed earlier; align with natural melatonin wave.
Bathroom trips Keep lights dim, return to bed quickly.
Racing mind 10 slow breaths (exhale 2× inhale) or brief body-scan meditation.

Quick Cheatsheet

  • Wake → log time → walk + sunlight → water + salt → delay caffeine.
  • Mid-morning → 90-min deep-work tunnel.
  • Late morning → workout (resistance or endurance).
  • Noon → protein-heavy meal, omega-3, post-meal walk.
  • Afternoon → sunlight break + second tunnel.
  • Evening → carb-rich dinner → hot bath → dark, cool room → optional sleep stack.
  • Always → skip large meals before work, hydrate, keep workouts < 1 h, alternate strength & cardio.

Master your 24-hour rhythm and everything—focus, mood, energy, sleep—gets easier.

Whoop CEO on Modern Wisdom

1. CrossFit’s Fumble & the Fitness Vacuum

  • Peak to Pit: CrossFit peaked ~2017-18, then stumbled (leadership scandals, partner dysfunction, poor event ops).
  • Opportunity Cost: Its fall opened space for Hyrox, boutique studios (F45, Barry’s, Orangetheory) & run-club culture.
  • Community Matters: Turning users into evangelists is CrossFit’s lost super-power—now fueling newer tribes.
  • Partner Pain: CrossFit labeled “most dysfunctional partner” in 13 yrs of WHOOP collaborations.

2. WHOOP: Inside the Data Goldmine

Metric Insight from 100k+ users
Sleep Only ~22 % log ≥7 h; consistency beats duration for health.
Global Quirks Doha avg. bedtime ≈ 2 a.m.; Ireland tops alcohol intake; Sweden & Finland lead cold plunges.
Activity Trends 2023 boom = pickleball (US); 2024 = padel (global).

3. Mindset & Self-Development

Only-Child Edge
  • Early adult interaction → comfort in big conversations.
  • Lots of solo time → innate inward reflection (helps define “what you truly want”).
Conviction vs. Doubt
  • Start-up reality: Years 21-24 were rejection-heavy; conviction in the idea carried Ahmed past shaky self-belief.
  • Separate Identities: Decouple company health from personal worth—avoid “chaotic founder” spiral.
Failure Philosophy
  • “Failure-porn” is overrated; unique successes teach more.
  • Yet taking any lesson (success or fail) expands resilience & emotional range.

4. Performance Playbook

Domain Ahmed’s Go-To Protocols
Morning Routine Wake → trainer workout → sauna → cold plunge → meditation → protein breakfast.
Travel Fast during flights; hydrate with hydrogen-infused water; slam electrolytes; align immediately to destination bedtime—no naps.
Jet Lag Mindset Much of it is psychological; stay positive, avoid alcohol & erratic sleep.

5. Recovery, Sleep & Tech

  • Hide the Numbers: WHOOP offers a toggle to collect but not display sleep & recovery scores—avoids “data anxiety.”
  • Combating Apnea: Breath-training tools (e.g., 15 min/day resisted-exhale devices) mimic wind-instrument benefits.
  • Hydrogen Water Wave: Portable H₂ flasks (e.g., Echo Go) and even hydrogen baths are emerging performance aids.

6. Ambition, Gratitude & Cost

  • Desire the lifestyle, not just the outcome (James Clear).
  • High achievers (Rory McIlroy, Ronaldo, Phelps) trade normalcy for relentless intensity—admire and audit the price.
  • Blend drive (dopamine) with gratitude (serotonin) to avoid “miserable successes.”

7. Practical Nuggets

  • Don’t eat on planes—fasting smooths circadian realignment.
  • Electrolytes + H₂O > airplane food.
  • Seek recurring fleeting thoughts to discover genuine goals.
  • State goals publicly, work hard consistently, embrace rejection—luck will find you.
  • Limit simultaneous desires; pick one or two lanes to go “all-in.”

8. What’s Next for Will Ahmed & WHOOP

  • New Features: WHOOP 5.0 offers 14-day battery, blood-pressure trends, AFib screening & “WHOOP Age” health-span score.
  • Scale new health-span, BP, and heart-screening features.
  • Prep for an eventual IPO.
  • Navigate new-dad life while keeping the morning ritual intact.

Evaluating Quality Supplements on the Dr. Hyman Show

1. Steve Martocci’s Transformation

  • Reached 300 lb in college despite two-a-day sports.
  • 2010: worked with a functional-medicine MD → thyroid Rx, hormone tuning, custom supplement stack.
  • Lost ~100 lb, founded tech hits (GroupMe, Splice); new mission = fix supplements.

2. Why Most Supplements Miss the Mark

Issue Reality check
Overwhelm > 200 k U.S. products; 8 k brands.
Loose regs 21 CFR 111 (self-policed GMP) ⇒ minimal FDA scrutiny.
Quality drift Filler dyes (e.g., titanium-dioxide), mislabeled doses, heavy-metal contamination, shady Amazon clones.
Doctor gap < 20 h nutrition training; many prescribe Mg oxide, D2, etc.

3. The Deficiency Epidemic

  • 90 % + Americans lack ≥1 nutrient at RDA floor.
  • Function Health labs (150 k members): ~70 % frank deficits at reference minimums.
  • Drivers: depleted soils, ultra-processed diets, RX drug leaching (statins → CoQ10; PPIs → Mg, B12).

4. Enter SuppCo

  • Catalog: 200 k products; barcode scan or AI label-upload.
  • 29-point “Trust Score” (0-10): 3rd-party cGMP, lot C O A, excipient flags, price-per-dose…
  • Sup Score: grades your stack for quality, cost, goal alignment.
  • 80+ Protocols: brain fog, fertility, heart health, women’s hormones…
  • Smart Scheduler: when/with food? pill reminders; soon tracks outcomes & side-effects.
  • Community: share stacks with MDs or socials; learn from n = 1 wins.

5. Partnering With Function Health

  • Lab data (vit D, omega-3, RBC-Mg, homocysteine, ferritin, etc.) feeds future personalized rec engine.
  • Goal: closed-loop—​test ⇢ prescribe ⇢ verify ⇢ iterate.

6. Stacks & Protocol Examples

Goal Core nutrients (sample) Why
Longevity Taurine 2 g, Urolithin A, NMN, Omega-3, D-K2 Mitochondria, autophagy, inflammation.
Prenatal Methyl-folate, choline, DHA, iron bisglycinate Neuro-dev, neural-tube, RBC support.
Detox / Fire Smoke NAC, Glutathione, Alpha-lipoic acid, Broccoli SFN Boost phase II, antioxidant load.

(Full protocol markdown inside Subco app.)

7. Drug–Nutrient Watch-outs

  • Statins ↔︎ CoQ10 depletion → fatigue, myopathy.
  • PPIs ↔︎ Mg/B12 deficiency → arrhythmia, neuropathy.
  • St John’s Wort ↔︎ OCP/SSRIs efficacy drop.

SuppCo will surface automatic interaction flags next release.

8. Cost & Ethics

  • SuppCo never profits on pill sales; aims to compress end-user prices via bulk & loyalty models.
  • Doctors can share stacks without “white-label” mark-ups—shifts focus from revenue to results.

9. Takeaways

  • Supplements aren’t going away—​but the Wild West is.
  • Data + transparent scoring empowers you to be CEO of your own health.
  • Test (Function), curate (SuppCo), track, and adjust; stop buying expensive urine, start buying measurable change.

Tweets

Jony Ive Teams Up With Sam Altman

  • Jony Ive started a new AI device company called IO a few years ago and they just got acquired by OpenAI
  • They will release more info about the device in 2026

Products

SuppCo

  • Look at the quality of your supplements
  • Understand if you’re taking too much of a nutrient across multiple supplements
  • Get expert guidance on ways to improve your supplement protocol